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Drugs for the Diseases of Aging

US Markets and Trends for Prescription Medicines Used
Predominantly by Persons Age 50 and older
Price: $ 1,495.00 (Hardcopy, Print Edition)
$ 2,295.00 (PDF Single-Department License)
$ 3,995.00 (PDF Corporate-Wide License)
Published: October 11, 2011
Total Page: 263 pages



This report reviews, analyzes and sizes the markets for prescription medicines used to address diseases and conditions that predominantly affect persons age 50 and older. It focuses on the large U.S. market, with five-year revenue projections to 2015. It also presents merger and acquisition activity, research and development (R&D) initiatives and venture capital activity for current and emerging drug developers.

Specific market segments examined include:

- Alzheimer's disease
- Arthritis
- Cancer
- Cardiovascular disease
- Diabetes
- Erectile dysfunction
- Eye disease
- Hair loss
- High cholesterol
- Hypertension
- Kidney disease
- Osteoporosis
- Parkinson's disease
- Stroke
- Wrinkles

In 2010, sales of these drugs used by exclusively persons age 50 and older were $50 billion. Through 2015, sales will expand by 5.3% per year to reach more than $64 billion.

On a segment by segment basis, medicines used for wrinkle reduction will exhibit the greatest growth at 17.7% per year, followed by drugs used to address Alzheimer's disease at 12.1% per year.

Historical information for this report was gathered from a wide variety of published sources including company reports and filings, government documents, legal filings, trade journals, newspapers and business press, analysts' reports and other sources. Interviews with company representatives and other experts were conducted to capture the perspectives from industry participants' point of view and assess trends, and form the basis of the forecasting and competitive analysis.

More than 200 detailed tables and figures provide key data about revenues and market size, market share and segments. Internet links help readers access companies' own web sites for further review.



Lists the major and emerging players discussed in this report:
5AM Ventures, Abbott Laboratories, Aberdare Ventures, ABM BioVentures, AC Immune, Acadia Pharmaceuticals, Accera, Actelion, Acuela, Adage Capital Management, Adolor, Addrenex Pharmaceuticals Advanced Cell Technology, Aegerion Pharmaceuticals, Aesthetic Factors, Affymax, AgeChem Venture Fund, Akebia Therapeutics, Alcon, Aldagen, Alexion Pharmaceuticals, Alimera Sciences, Allergan, AlloCure, Alta Partners, Amgen, Amorcyte, Angion, Anteis, Arena Pharmaceuticals, Apricus Biosciences, Aravis Venture, Ariad Pharmaceuticals, Astellas, AstraZeneca, Athersys, Atlas Venture, Aurobindo, Aurora Funds, BankInvest Biomedical Development, Baxter, Bayer, Bellus Health, BioLineRx, Biovail, Boehringer Ingelheim, Bristol-Myers Squibb, Brookside Capital Partners, Caxton Advantage Life Sciences Fund, Cellgate, Celtic Therapeutics, Cephalon, Charter Life Sciences, Cipla, Clarus Ventures, Colt Ventures, CoMentis, Contura, Cortica Neurosciences, Cristalia Pharmaceuticals, Cure Alzheimer's Fund , CrystalGenomics, Cytori, D-Pharm, Daiichi Sankyo Co., Ltd., Delphi Ventures, Depomed, Domain Associates, Dong-A PharmTech Co., Dr. Reddy's, Edmond de Rothschild Investment Partners, EKR Therapeutics, Elan, Eli Lilly, EMBL Ventures, Endo Pharmaceuticals, Essex Capital Corporation, Essex Woodlands Health Ventures, Eyetech, Fibrex Medical, Fibrocell, Fibrogen, Flagship Ventures, Forest Laboratories, Furiex Pharmaceuticals, Gauss Capital Advisors, Genaera Corp., Genentech, GenVec, Genzyme, GlaxoSmithKline, Glenmark, Global Life Science Ventures, Goldman Sachs, Greylock Partners, Hamilton BioVentures, Hikma Pharmaceuticals, Horizon Technology Finance, Hospira, Humanetics, Index Ventures, Intersouth Partners, InterWest Partners, Investor Growth Capital, Isis Pharmaceuticals, Jerini Ophthalmic, Johnson & Johnson, KAI Pharmaceuticals, Kaylight, Kearny Venture Partners, Leader Ventures, Ligand Pharmaceuticals, Logical Therapeutics, Luitpold Pharmaceuticals, Lupin, Macuclear, MDS Capital, Medicis, Mediphase Venture Partners, Merck, Merz, Mithridion, Monarch/King Pharmaceuticals, MPM Asset Management, MPM Capitol, Mulligan Biocapital, Mylan, Nanotherapeutics, NeoStem, NeuroDerm, Neurologix, NeuroVentures, New Enterprise Associates, New Leaf Venture Partners, New Ventures, NicOx, Nordic Bioscience, Northern Therapeutics, Novartis, Novitas Capital, Novo Nordisk, Novogyne, NPS Pharmaceuticals, Nuvo Pharma, Och-Ziff Capital Management, Ono Pharma, Opexa Therapeutics, Ophthotech, Opko Health, OrbiMed Advisors, Orion, Osiris Therapeutics, Othera Pharmaceuticals, Oxigene, Pac-Link, Paladin Capital, Pharma Two B, Phytopharm, Palatin Technologies, Paloma Pharmaceuticals, Par Pharmaceuticals, Pfizer, PledPharma, Pozen Pharmaceuticals, Prairie Gold Venture Partners, Prana, Purdue Pharma, Prospect Venture Partners, PureTech Venture Partners, QLT Ophthalmics, Quaker Bioventures, QuatRx Pharmaceuticals, Ranbaxy, Regado Biosciences, Regeneron, RegeneRx Biopharmaceuticals, Relypsa, RepliCel, Revance, Rexahn Pharmaceuticals, Ridgeback Capital, Roche, Rocket Venture Fund, Rosewood Corporation, Roxane, RXi, Sanderling Ventures, Sandoz, Sanofi-Aventis, Santaris Pharma, Santarus, Satori Pharmaceuticals, Scale Venture Partners, Seattle Genetics, Shepherd Ventures, Sigvion Capital, Silicon Valley Bank, Skyline Ventures, SMBC Capital, Somerset, Sonexa Therapeutics, Sprout Group, Stealth Peptides, Stem Cell Therapeutics, Stemedica, Sucampo Pharmaceuticals, SV Life Sciences, Swiss Helvetia Fund, Sygnis Bioscience, TargeGen, TauRx, Technology Partners, Tekmira Pharmaceuticals, Teva, The Medicines Company, Thomas Weisel Venture Partners, Thrombogenics, Triathlon Medical Ventures, UCB Pharma, Unigene, Valeant, VCFA Holdings, Venture Investors, Versant Ventures, ViVo, Vivus, Warner Chilcott, Watson, Zalicus



Table of Contents


Executive Summary
1. U.S. Drug Market Overview and Trends

  1.1 U.S. Drug Market by Segment for All Ages, 2010 - 2015
      Table 1.1: Total U.S. Market for Drugs of Aging (All Ages), 2010 - 2015, in Millions
      Table 1.2: Total U.S. Market for Drugs of Aging (All Ages), by Segment, 2010 - 2015,
                  in Millions
      Figure 1.1: Total U.S. Market for Drugs of Aging (All Ages), Segment Share in 2010
      Figure 1.2: Total U.S. Market for Drugs of Aging (All Ages), Segment Share in 2015

  1.2 U.S. Drug Market by Segment for Aged Population, 2010 - 2015
      Table 1.3: Total U.S. Market for Drugs of Aging (Aged Population), 2010 - 2015,
                  in Millions
      Table 1.4: Total U.S. Market for Drugs of Aging (Aged Population), by Segment,
                  2010 - 2015, in Millions
      Figure 1.3: Total U.S. Market for Drugs of Aging (Aged Population), Segment Share
                  in 2010
      Figure 1.4: Total U.S. Market for Drugs of Aging (Aged Population), Segment Share
                  in 2015
    1.2.1 Market Size and Forecast
        (Include Table 1.5-1.19)
    1.2.2 U.S. Sales of Drugs and Share for the Diseases of Aging
      1.2.2.1 Alzheimer's Disease
      1.2.2.2 Arthritis
      1.2.2.3 Cancer
      1.2.2.4 Cardiovascular Disease
      1.2.2.5 Diabetes
      1.2.2.6 Erectile Dysfunction
      1.2.2.7 Eye Disease
      1.2.2.8 Hair Loss
      1.2.2.9 High Cholesterol
      1.2.2.10 Hypertension
      1.2.2.11 Kidney Disease
      1.2.2.12 Osteoporosis
      1.2.2.13 Parkinson's Disease
      1.2.2.14 Stroke
      1.2.2.15 Wrinkles

  1.3 Market Drivers
    1.3.1 U.S. Demographic Data for the Entire Population and Aged Population:
                  the Effect of Aging
      Table 1.20: U.S. Demographic Data (Age) and Trends in Millions of Persons
      Table 1.21: U.S. Demographic Data (Age) and Trends for Aged Population
                   in Millions of Persons
    1.3.2 U.S. Demographic Data for the Entire Population and Aged Population:
                   the Effect of Obesity
      Table 1.22: U.S. Demographic Data (Obesity) and Trends
                  in Millions of Persons
    1.3.3 U.S. Demographic Data for the Entire Population and Aged Population:
                  the Effect of Rising Medication Usage
      Table 1.23: U.S. Usage of Prescription Medicines Each Year
                  in Millions of Persons

  1.4 Advanced Biotechnology
    1.4.1 Overall Trends
    1.4.2 New Trends and Personalized Medicine
      Table 1.24: Total U.S. Sales of Personalized Medications, 2009 vs. 2010
      Table 1.25: Pipeline for New Personalized Medicine by Segment

  1.5 Market Restraints for the Diseases of Aging
    1.5.1 Rising Usage of Generics
      Table 1.26: U.S. Usage of Prescription Generic Medicines vs. Branded Medicines
                   by Segment

  1.6 New Products
      Table 1.27: New Product Information by Segment

  1.7 Leading Manufacturers, New Companies and Venture Companies by Segment
    1.7.1 Leading Manufacturers
      Table 1.28: Leading Manufacturers of Branded Prescription Medicines Used
                  by the Aged Population
      Table 1.29: Leading Manufacturers of Generic Prescription Medicines Used
                  by the Aged Population
    1.7.2 Personalized Medicine Manufacturers
      Table 1.30: Leading Manufacturers of Personalized Medicines Used by the Aged Population
    1.7.3 New/Emerging Manufacturers
      Table 1.31: New/Emerging Manufacturers of Medicines Used by the Aged Population
    1.7.4 Venture Companies
      Table 1.32: Venture Companies Involved With Medicines Used by the Aged Population

2. Individual Drug Product Market Trends and Directions
       (Include Table 2.1-2.132)
   Common Research Items:
    1) Market Size for U.S. Aged Population, 2010 - 2015
    2) Drug Sales and Share, 2010 vs. 2012
      - Branded Drug Sales and Share, 2010 vs. 2012
      - Generic Drug Sales and Share, 2010 vs. 2012
    3) Pipeline Drugs
      - Pipeline for New Branded Drugs
      - Generic Drugs
    4) Personalized Medicine
      - Current Personalized Medicine
      - New Personalized Medicine Pipeline
    5) Major M&A Activity by Companies
      - Leading Company R&D for Drugs
      - New Company R&D for Drugs
      - Venture Company R&D for Drugs

  2.1 Alzheimer's Disease
  2.2 Arthritis
  2.3 Cancer
  2.4 Cardiovascular Disease
  2.5 Diabetes
  2.6 Erectile Dysfunction
  2.7 Eye Disease
  2.8 Hair Loss
  2.9 High Cholesterol
  2.10 Hypertension
  2.11 Kidney Disease
  2.12 Osteoporosis
  2.13 Parkinson's Disease
  2.14 Stroke
  2.15 Wrinkles

3 U.S. R&D Activity and Road Map for Future Direction by Market Segment
      (Include Table 3.1-3.15)
  3.1 Alzheimer's Disease
  3.2 Arthritis
  3.3 Cancer
  3.4 Cardiovascular Disease
  3.5 Diabetes
  3.6 Erectile Dysfunction
  3.7 Eye Disease
  3.8 Hair Loss
  3.9 High Cholesterol
  3.10 Hypertension
  3.11 Kidney Disease
  3.12 Osteoporosis
  3.13 Parkinson's Disease
  3.14 Stroke
  3.15 Wrinkle Reduction

4. Positions, Alliances, Patent Issues and R&D Strategies for Leading Manufacturers
  4.1-4.40 (total 40 manufacturers)

5. Important Findings and Recommendations for Business Opportunities
  5.1 Generics
  5.2 Indication Expansions
      Table 5.1: Pipeline for Indication Expansion Opportunities
  5.3 Personalized Medicine

6. Appendix
  6.1 Selected Companies Mentioned in this Report
      Table 6.1: Major Developers of Prescription Medicines for the Aged Population

    

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